Open the menu, in game, select Controls or Options. Typing Escape again will open the main menu again, blended in the current menu.
Also, moving from one room to another, sometimes the black screen is taking too long. At least, the delay is inconsistent.
setup: Windows 10 1803 64 bit, AMD RX480 8GB, Radeon 19.2.1.

On the factory level, on the second floor tried to combine bottle with the cloth, and then it glitched-teleported into the room with instruments. And after that Lorelai can't move left, only right, so i can't get to the room with the bottle.

This has already been fixed with an update published on Steam two days ago. Unfortunatly GOG is just damn slow at delivering updates.
I should remember for next time, never buy freshly released games on GOG.

Okay, I've had a game breaking bug as well. Got to start of chapter 4, asked about the "Dog Gentleman" game and was shown a pixel style landscape which did nothing, could not be escaped, and wouldn't respond to any control input whatever. And it had autosaved just beforehand.

Ugh. Time to go back to the start.

Any chance of a fix?

All kinds of weird Glitches in the Factory. For a while Lorelai was invisable and she the I saw option to use the workbench but couldn't see the character. Then it teleported me out of the room. BUT The most game breaking is after using the bottle with Fertizlizer Lorelai can no longer walk Left. WTF. Left work in the inventory but not in the walking. Another one right before that. Lorelai said John was in the shipping crate but he's just standing in the middle of the yard and I can Saunter right past him. I really hope we get a patch soon. I was loving this game and now I'm totally stuck because Lorelai can't walk Left. :-(

The game crashes at chapter two in the house on the woods.
This "Ooops" message makes me wanna hurt someone...

Should I ask for refund already?

Actually the developer did an insanely great job at putting out a whole lot of bug fixes in no time. Unfortunately with GOG being on national holidays there was nobody to make the updates public here and you ran into issues that might likely already have been fixed in the Steam version.

The latest update is finally released here on GOG.

I'm sad to say that it still crashes...

Also have a bug on Chapter 4 dog gentleman scene.. it stuck in the game with the background can't move, and it autosaved so cant go back. Can someone upload a save from start of chapter 4 or end of chapter 3 so I can revert?

Lorelai keeps walking left by herself if my PS4 contoller is connected to my PC. I have to unplug it every time when I want to play. It is not a huge issue, but kinda annoying.

Having an issue where nothing is visible on screen after exiting the kitchen to see the queen of maggots. I have the feeling that dialogue options are available because I hear talking but nothing is on the screen.