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Had a crash in Dom's office after getting back from the poisoning. After talking to Dom, I walked over to his computer area and tried to access it and he said, "Stay away from my computer Manny" and I just stood there for a few minutes and then it froze up but you could still hear Dom jabbing away at the speed bag.

Must be more likely to crash when multiple animations are playing at the same time. Dom was jabbing the speed bag and Manny usually lights up a cigarette when he stands idle for a period of time.