If you're having trouble with a boss, then make sure you're doing a few things...
Upgrade your heros. Probably up to 100 each, it unlocks almost all their abilities.
Use your skills together, although clickstorm is helpful, the double damage and critical from the assassin is far more valuable.
When a new hero is available, take him up right away. Their damage is usually 10-100x more than the previous hero.
If you plan on having a long run/game, use dark ritual, adds 5% damage for that run. 10% if you charge it first :P
Feel free to use a auto-clicker/auto-fire script or program, and use it sparingly (when you need a little boost on bosses for example
) no need to wear your mouse out.
I'll post a few pics when i get to level 100 with the hamster, and when i have the slot unlocked for ascension.
I did find a fish. I don't know what that does, though.
If you see weird stuff, click on it. If it doesn't react, click more (about 50 times).
hmmm the icon changes.. Sometimes it's a bag, a fish, a snowflake, an orange... curious that it keeps changing... Reminds me.... Here's a little fun pic i got :P