If F2 would run on dosbox I would at least be able to run it. I haven't found any working solution to run it on my mac. There used to be some ports, but can't get them to work. Too bad.
This is a bit lazy suggestion, but you could try this (and let us know if it works).
I'd try it myself, but ... lazy. WineBottler
Any other WIne solution might work just as well. Crossover almost certainly, but it's not free.
I know VirtualBox
worked for the stuff I tried it with, but you need windows install discs for that.