fisk0: Also having this issue, on a Windows 10 machine with a GTX 1050 TI.
I'm using a regular Microsoft Basic Optical Mouse, so it shouldn't be a mouse DPI issue either (I know modern gaming mice with DPI switches often cause problems in games from this era).
It seems like I'm actually moving a cursor around, but it isn't shown, as I managed to enter the settings menu at one point by moving the mouse around and clicking.
EDIT: I managed to get it working through these steps:
1. Go to the install folder (Galaxy has a shortcut under More > Manage Installation)
2. Right click Empires_DMW.exe and go to properties
3. Click the compatbility tab and the "Change settings for all users button" at the bottom
4. Check "Run program as administrator", "Disable full screen optimization" make sure "Disable DPI scaling set by:" is checked at set to "System (extended)" rather than the default "Program".
5. Apply and close the window and try launching the game again.
It's weird that we have to go through these steps since this is basically what GOG are supposed to do when they rerelease older titles, but I got it working through these steps.
I followed these steps, but I'm still having some issues, and wondered if anyone else had any suggestions. Windows 10 machine as well. (If it makes a difference, I'm running Windows 10 through Parallels on a 2016 15" MacBook Pro. I can get some other older games to work fine.)
When I make these three changes to the compatibility settings, I can move the cursor (and it becomes much smaller, more like my standard cursor rather than the huge thing that was frozen in the center of the screen before I made these changes), but there's no response when I click on any of the menu options.
If I set the DPI override to "System" rather than "System (Enhanced)" I can click on things and proceed through the menus (e.g., click on "Single Player" and get to the next screen), but I can only see the top left corner of the screen (everything is blown up), and can't scroll past those edges. Thus, I can enter my name, but can't start a game or do anything else. If I uncheck the "Override high DPI scaling behavior box," I can click on things, but the cursor doesn't move, so I can't see what I'm clicking on.
Moreover, Windows keeps trying to update the compatibility settings every time I exit the program, resulting in a return to the frozen-cursor-in-the-center-of-the-screen state. (Looking through the compatibility settings afterwards, though, I can't figure out what settings it's changing.)
Any suggestions?
UPDATE: I'm still having issues, but I figured out that the cursor can click on things with the new settings, but it isn't aligned properly. For example, from the Single Player menu, clicking somewhere on the "Richard Lionheart" campaign button actually clicks on the box for name entry. I'm also still having issues with Windows resetting my settings after every use in an attempt to enable compatibility (resulting in the frozen/invisible cursor issue).