It seems that you're using an outdated browser. Some things may not work as they should (or don't work at all).
We suggest you upgrade newer and better browser like: Chrome, Firefox, Internet Explorer or Opera

ggzx12: Did you try to deactivate the user account control system?
Did you try to exclude the game from the data execution prevention?
Did you try to run the game as administrator?

Modern OS' behavior is usually disturbing for old games.

Anyway, if it does not work, at least, you can reinstall the game in a different place (as the problem is specific to the actual path of the game).
777Shot: Bingo, I ran the game as administrator and save now works. Amazing. You resolved my music issue and my save game issue. Thank you very much.
You're welcome.

Wish you a happy Dark Reign! ;)