I attached an image of where I am stuck. I checked a walkthrough and a video walkthrough so I know I'm supposed to hit the red orb with the floating thingies, but they're so difficult to direct that the mere attempt drives me crazy and is ruining the game for me. Any tips on how to proceed? Not with anger management but with making the red orb go where I want it to.

You don't need to use other balls, just try to chase red one with your mouse, kind of like not touching it, but bumping it into right direction.

Thanks you so much grviper. I'll send Amanita a message about the problem with fullscreen here, though likely someone already did.