Kangaxx: Only with AMD Crossfire: No targetting reticule/health bar when attacking/interacting with certain NPCs
Problem: When your graphics card is running on AMD Crossfire technology, no targetting reticule and health bar appears when fighting certain enemies (e.g. Endregas, Wraiths,...) and interacting with such NPCs (like at the end of In the Claws of Madness) is impossible as well.
Procedure: Just have an AMD Crossfire card and the latest drivers installed.
Workaround: Rerolling to CAP2 11.6 seems to be a solution, but this screws over other games and general Witcher 2 performance.
Thread: CAP problems In the Claws of Madness bug
Status: The issue was fixed in a CAP release by AMD some months ago, but either they accidently rerolled it in newer CAPs or the 2.0 patch broke it again.
What the deuce? So that explains it. Crossfire turns out to be more a curse than a blessing.