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I just keep deleting them from the directory. Its like User/Documents/Wither 2/gamesaves I think.
Lol. I just started my second playthrough and I have 428 items in my Witcher 2 Save Game folder. Since it generates two files per save (save file + BMP file), that's basically about 219 saves for one play through. Gosh. I didn't think I quick saved THAT much. :/