groze: Well, I'm installing it now, so I'm not aware of the possible bugs and glitches of this version, but I played Sanitarium for a lot of years, now, from my original CDs of the game and I never had any issue whatsoever. Granted, I don't have a computer with Win 7 or 8, but I never had any issue playing it on Win 98, 2000, XP and Vista. Once I have the GOG version installed I'll update this post, but I'm pretty confident the game will run smoothly.

Even if it has some bugs and glitches running on some machines, you guys shouldn't complain this harshly, because this truly is an underrated, overlooked piece of video gaming art and a lot of people may be put off by all of the posts complaining about some issues instead of talking about, I don't know?, how good this game is, perhaps?

EDIT: Ok, I've been playing it for an hour and a half, now, and encountered no bugs whatsoever. There's no color glitch, no crashing, nothing... I'm truly sorry for all you guys having trouble running the game, but I encountered no issue during this first hour with it... still as good as I remember it, running smoother than my boxed copy, with shorter loading times and better control sensitivity.

tfishell: GOG recently updated their build to support the latest OSes. Maybe that helped.