I'm running 7 Home Premium 32. Fallout, Divine Divinity, and Dark Fall: The Journal work well. Broken Sword 2 has a major glitch, but I'm doubtful that it's related to the OS.
Opinion side-note: I use Windows 7 on my cheapo laptop and like it a lot, but I can't really afford the $110 it'd cost to upgrade my only gaming-quality PC from XP to 7. Aside from that, I'm afraid it'd bork things beyond repair and would require a fresh install, which I have absolutely no idea how to do.
Post edited March 11, 2010 by ACDude800