If you have reason to suspect them, yes. As Rod said, if they get replaced then it's easy to lose track of suspicions. Basically: if you think someone should be lynched and they're in danger of being replaced, it's best to do it before they get replaced.
I disagree with this. I would need a hell of a reason to lynch someone who is going to be replaced. Like G 9 reason. Otherwise it just gives free pass to mafia to lynch someone for something that victim can't explain and defend against. Something that can be just misunderstanding. If it is cop result of someone caught lying then of course, it's usually not worth the hassle but otherwise... I don't think so.
I'm sorta in agreement with the idea, sorta not, and I'll explain.
If they were obviously being suspicious, and then when the votes were piling up they started asking for a replacement, then finish the lynch. This isn't such a case, the most suspicious thing that Penut did was well, not post, and there have been a few people who have been lurking at this point.
It's day 1, Penut hasn't really said anything and the worst he's done is lurking. Any replacement would have to be more active, and a more active person would get us something to work with.
Argh, there have been too many people who have been way too quiet lately, and it's actually bugging me a lot.