Though this is a little ahead of schedule:
I always wanted a movie AND game version of Ender's game.
I think i heard that both are in the works. I think EG wuld make an awesome movie.. and while the real world stuff probably wouldn't work as a game, i always wanted an RTS that controlled like the game in Ender's Game... fast, fluid, about timing, feints and picking weak spots.
Homeworld meets Darwinia maybe...
The thing about most games is that the GAMEPLAY is mostly gruntwork. The gameplay generally revolves around repeating the same few actions a lot until a cutscene apears and actually advances the plot. Hence the only parts of games and movies that are often compatible are the cutscenes.
Also, most gaming settings and characters tend to be generic stereotypes. This is intentional, as gamers usually (MGS apart) don't want to sit through lots of cutscenes and exposition building up characters. So a stereotypical character can be introduced and understood much more efficiently by the game designers.
But this means most games don't translate well into movies, where there needs to be more depth and more originality. Characters from fighting games, for example, tend to look stupid in real life. Games like Doom, Halo, Half Life, etc.. are all essentially based on the generic Aliens idea. Those kind of settings and characters work well in a game... heck, Doom didn't even need cutscenes.. we instinctively knew who the player was, as we'd encountered them so often before in fiction.
Even the most generic or average blockbuster movie (eg: Stealth, Blade, Riddick) tends to have way more character depth, interaction and development than most of the deeper video games. Different needs, standards and expectations. Depth in games comes in terms of gameplay mechanics.
System shock 2 is one of my all time favorite games, has great atmosphere, a memorable villain, and great depth and mechanics... but nothing in it (with the possible exception of the villain) would translate well into a movie... and even if it was done, and done well, it'd just be a generic scifi movie.
Interstate 76 directed by Quentin Tarantino...