Hi again, I've just had a play on Fallout again, this time attempting to follow Paul-cz's advice!
I'm no expert so I have to admit, I'm not 100% on the programs/files you mentioned there. However, I closed down Skype and all additional, unnecessary programs in my system tray. In about 40 minutes of play, I only had 1 blackout, so perhaps, it is more to do with the items you named.
Sorry I couldn't be more help to you this time!
good to hear that some of it helped. :D