If you talk about Earth 2150, set sound to Software via setup:
Start -> Programs -> GOG.com -> Earth 2150 Trilogy -> [name of the game] -> Setup
Had the same issue when setting it to Hardware.
PS: I only find that option in Escape from the blue Planet. No idea if it is natively in LS and TMP since I installed patch 2.2 for both before I started it.
Yea that worked, thanks a lot.