I have a bizarre problem which I never encountered using the CD-based versions of the games represented under the Earth 2150 Trilogy under Windows 7 (at least the first two games - I've never actually played "Lost Souls" on Windows 7) When I attempt to design a unit in-game, the game immediately crashes. There are no specific circumstances - simply boot up the game, start a battle, and click on the "Construction Center" button. It doesn't matter whether I launch the game using the supplied shortcuts or the games' executables, and changing compatibility options doesn't do anything, either.
I have the same problem, playing on win 7, when i press F1 ( design ) it crashes. Did you solve it !
And it wont play full screen mode.