what OS x version are you running & which version of eduke?
you may have to down grade/ up grade to match up requirements
try these pages for info: http://www.spam-filter.de/osx/eduke32_on_os_x http://www.spam-filter.de/?ns=osx%2Feduke32%2Farchive&tab_files=files&do=media
I'm on 10.7.5 and I'm running the latest version of eduke32.
EDuke32 2.0 Universal (Version 2013-01-15, svn3393)
Is there a newer version? Basically, the forcesetup tag in the eduke.cfg is being ignored.
I tried installing the latest (previous?) lion build: eduke32_osx_leopard_svn3381
But that exhibited the same behavior. Even if I select "show setup window at start" while running eduke,and then quitting. It still doesn't show the startup window on restart. Eduke does change forcesetup to 1 or 0 depending on my setting in the program (game setup screen), but it has no effect when I start up eduke again.