I don't think anyone has mentioned Vampire -The Masquerade: Bloodlines. Sadly it's not available here on GOG.com so far, but it's a pretty amazing cRPG. It's a first/third person real-time action cRPG, so it's very, very different from Arcanum, but like Arcanum it was made by Troika.

It takes place in modern day (well, modern as of ten years ago) Los Angeles in White Wolf's World of Darkness setting. You don't have to be in to vampires to appreciate it, either.

Yes, Vampire: The Masquerade needs to be here.

You have to be careful though, because there's Vampire - The Masquerade: Redemption, which is an older game available on GOG.com (though I haven't played it personally).

Then there's Vampire - The Masquerade: Bloodlines, which is the ten-year-old Troika game NOT available on GOG.com. Bloodlines is the one I'm talking about.

certainly, the Troika one is the one that matters, not that other thing

The Cyberpunk setting in Shadowrun is pretty cool.

Yeah those games look really interesting! I'm excited to try those eventually because of the setting/atmosphere/story appeal.

Definitely try out Dragonfall. The companions are great.

(sadly)shadowrun for the genesis/megadrive(in 1994?) is probably the best adaptation of that gaming system ever made.

Age of Decadence is reportedly going to be released here on GOG.com in the middle of October. It might not appeal to everyone, but it's going to be legendary nonetheless.

Oooya, that looks interesting for sure, I will keep an eye for it coming here, thanks~!

That game is finally getting a real release? I remember hearing about it years ago but would totally check it out.

Here are my thoughts:

Dragon Wars: This game's setting is what I would call a fantasy dystopia. The ruler is evil, magic has been outlawed (well, not totally), and much of the world is under said ruler's control. It's interesting to note that, while dragons exist, they were added late in the game's development. No race is chosen for PCs, although dwarves exist (albeit as statues). This game is also notable for having multiple solutions to puzzles (especially escaping Purgatory, the prison town in which you start), and for having a spell that many developers make not work where it would be most useful, but actually making said spell work where you wouldn't expect.

Morrowind: Of all the Elder Scrolls games, this one has the most atypical setting. There are elves (playable) and a dwarf (not playable), but the game doesn't feel like a standard fantasy setting. The game world actually feels rather alien with its mushroom forests and rocky terrain. Also unusual is that this is not a human majority setting; it is the Dark Elves who are the natives of this land. (Unlike in Dungeons and Dragons, Dark Elves (Dunmer) aren't inherently evil.) Also notable is that two of the playable races are essentially animal races complete with tails.

Ultima 1: Fantasy with a bit of science fiction thrown in. You get blasters, air cars, and even a rocket that sends you into space in this game. Be aware that the game is rather primitive. (Hint: The first place to go after getting starting equipment is the nearest dungeon; it is better to fight there than outside because leaving a dungeon gets you hit points based on the enemies killed.)

From the horse's mouth:

http://www.irontowerstudio.com/forum/index.php/topic,6807.0.html

Yes, it's been in development for ten years.

SanctuaryRPG: Black Edition- The world feels somewhat normal at first, but after a little bit of playing things get interesting. It's also pretty good at letting you use your imagination to fill in the blanks. Keep in mind though, it has a good bit of little things you can do but it's more combat oriented. It's also a Roguelike hybrid so expect death.

Tales of Maj'Eyal/ToME 4- More of a classic Roguelike instead of a mix. It has your Elves/Dwarves/Halflings sure, and it was before the 4th version in Middle Earth so expect the surface to be typical. But if you get a little bit more into the game, even only after unlocking some certain classes/races, things set themselves up have some pretty atypical twists. Especially with the DLC and how it views what a demon is. Subsequent playthroughs can give you completely different views of the world depending on what setup you choose too, so multiple times playing aren't always as dull as they seem.