I was trying to kill a bunch of super mutants and had low health so i was saving and reloading alot because i wanted to cheat the odds a little. I wasnted to kill a certain mutant in one shot. However after loading and reloading a couple times it corrupted my save file. the bad thing is this is the only save file i had after i beat the game.

Do not save during combat. The game has always had random crashes it you do this.